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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Collagen-VI supplementation by cell transplantation improves muscle regeneration in Ullrich congenital muscular dystrophy model mice

Fig. 7

UCMD-iMSC transplantation experiments. a Sectional images of TA muscle 2 weeks (tx2w, left 2 columns) and 12 weeks (tx12w, right 2 columns) after UCMD-iMSC transplantation. b Quantitative data of the COL6-positive area per whole TA muscle CSA 2 and 12 weeks after the transplantation. Data are shown as the mean ± SD. n = 6 (2 weeks), n = 6 (12 weeks). **P < 0.01. c CSA per muscle fiber in the TA muscles of Col6a1KO mice 2 and 12 weeks after medium injection or UCMD-iMSC transplantation. Data are shown as the mean ± SD. n = 3. n.s., not significant. d Number of muscle fibers in the TA muscles of Col6a1KO mice 2 and 12 weeks after medium injection or UCMD-iMSC transplantation. Data are shown as the mean ± SD. n = 3. n.s., not significant. e Sectional images of TA muscles 1 week after medium injection or UCMD-iMSC transplantation. f Number of eMHC-positive fibers 1 week after medium injection or UCMD-iMSC transplantation. Data are shown as the mean ± SD. n = 3. n.s., not significant. g CSA per eMHC+ muscle fiber in the TA muscles of Col6a1KO mice 1 week after medium injection or UCMD-iMSC transplantation. Data are shown as the mean ± SD. n = 3. n.s., not significant

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