Fig. 2
ADSCs alleviate radiation-induced skin damage in radiation-induced dermatitis rat model. Female rats were irradiated with 90 Gy and injected with PBS (control group, n = 12) or were irradiated with 90 Gy and injected with 107 ADSCs (ADSC group, n = 12). Representative images of the skin from day 5 to day 84 post-irradiation are shown. Skin damage was semiquantitatively scored from 1 (no damage) to 5 (severe damage). A Rats in the ADSC group had smaller ulcers and open wounds at 3, 4, and 5 weeks post-irradiation than the control rats (red dotted line) (n = 12). B Skin damage scores were lower in the ADSC group than in the control group at 3 to 5 weeks post-irradiation, as indicated by the green dotted line (n = 12). The results are expressed as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001 vs. the control group