Fig. 3

ADSCs alleviate radiation-induced dermatitis in vivo. Representative images of hematoxylin and eosin-stained skins from rats in the control group at 4 weeks (A) and 12 weeks post-irradiation (C) and the ADSC group at 4 weeks (B) and 12 weeks post-irradiation (D). Yellow curves indicate skin appendage loss. The red line indicates epidermal thickness. The green arrows indicate blood vessels. Green circles mark infiltrated lymphocytes. Statistical analysis of epidermal thickness, dermal thickness, hair follicle density, migrating hair follicle density, sebaceous gland numbers, and lymphocyte number per 400× field in each group (E) (n = 8/group). The results are expressed as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001 vs. the control group. H hair follicle, S sebaceous gland, C collagen