Fig. 8

ADSCs downregulate the expression of CTSF, BAX, Bid, and caspase 9 and upregulate that of Bcl-2 and Bcl-XL in radiation-induced dermatitis model rats in vivo. Representative images of skin tissues immunohistochemically stained for CTSF (A). Representative blots of CTSF, BAX, Bid, Bcl-2, Bcl-XL, and caspase 9 levels in skin tissues (B). GAPDH was used as a loading control. Average OD of CTSF (C) (n = 6/group). Protein expression level analysis (D) (n=4/group). I, control-4w; II, ADSCs-4w; III, control-12w; IV, ADSCs-12w. The results are expressed as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001 vs. the control group