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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Bone marrow mesenchymal stem cells promote remyelination in spinal cord by driving oligodendrocyte progenitor cell differentiation via TNFα/RelB-Hes1 pathway: a rat model study of 2,5-hexanedione-induced neurotoxicity

Fig. 7

NGF and its relationship with TNFα expression in HD/BMSC-CM-treated OPCs. a, b Western blot results showing the level of NGF, p-TrKA and TrKA in HD/HD + BMSC-CM-treated OPCs. c Western blot results showing the level of TNFα in HD/HD + BMSCs-treated OPCs receiving additional interference with NGF neutralizing antibody (anti-NGF), negative control antibody (anti-NGF-Ho) or recombinant NGF. d Western blot results showing the level of TNFα in HD/HD + BMSCs-treated OPCs without or with TrkA inhibitor K252a treatment. a: Compared with control group, p < 0.05; b: compared with HD group, p < 0.05; c: compared with HD + BMSC-CM group, p < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512