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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: RETRACTED ARTICLE: GDF11 enhances therapeutic functions of mesenchymal stem cells for angiogenesis

Fig. 4

The paracrine effects of MSCsGDF11 on HUVEC. A Transwell assay of HUVEC after cultured with the conditioned media (CM) from specified MSCs (NC: CM from MSCvector; GDF11: CM from MSCGDF11) for 24 h. B Quantification of migrated HUVEC. Cells that migrated to the lower chamber were counted (n = 3 in each group). C Representative images of tube formation of HUVEC on Matrigel cultured with the conditioned media from specified MSCs (NC: CM from MSCvector; GDF11: CM from MSCGDF11). Scale bars: 200 μm. D The tube length in B was assessed, length > 200 μm was counted. n = 5. E Representative images of migrated MSCvector and MSCGDF11 in a transwell assay. Scale bars: 200 μm. F Quantification of MSCs that migrated to the lower chamber (n = 3 in each group). *p < 0.05; **p < 0.01 and ***p < 0.001

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