Fig. 6.

0.25 L versus 50 L STR results. a Diagram of our “split stream” growth where 1 donor was grown in both small scale and pilot scale reactors b Comparable sphere growth observed in small scale and pilot scale reactors. Sphere size c is comparable at harvest. d Aggrecan expression is below the qualified limit of detection for both conditions. e Cell doublings from day 2 to end of culture across 0.25 L and 50 L STR are comparable. f Identity and purity of cells as measured by Flow cytometry is comparable between 0.25 L STR and 50 L STR