Fig. 2

Fusion index and hybrid myotube presence in either human bone marrow-derived mesenchymal stromal cells (hMSC) or pig bone marrow-derived mesenchymal stem cells (pMSC) co-culture with myoblasts: mouse primary myoblasts (mPM) or C2C12 myoblasts. A Fusion index of mPM and hMSC or pMSC co-cultured in MSCmed or PMmed under normoxic (NORM) or hypoxic (HYPO) conditions. B Fusion index of C2C12 myoblasts and hMSC or pMSC co-cultured in 3:2.5; 3:5; 3:7.5 ratio, in C2C12med, under normoxic (NORM) or hypoxic (HYPO) conditions. C Percentage of hybrid myotubes in mPM and hMSC or pMSC co-cultures in MSCmed or PMmed under normoxic (NORM) or hypoxic (HYPO) conditions. D Immunolocalization of hybrid myotubes in mPM and hMSC co-cultures, red—skeletal myosin, blue—cell nuclei, green human cell nuclei. E Percentage of hybrid myotubes in C2C12 and hMSC or pMSC co-cultures in C2C12med under normoxic (NORM) or hypoxic (HYPO) conditions. F Immunolocalization of hybrid myotubes in C2C12 and hMSC co-cultures, red—skeletal myosin, blue—cell nuclei, green—human cell nuclei. P value: *< 0.05; **< 0.01; ***< 0.001; ****< 0.0001