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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: A novel RIP1/RIP3 dual inhibitor promoted OPC survival and myelination in a rat neonatal white matter injury model with hOPC graft

Fig. 3

ZJU-37 combined with hOPCs improves behavioral function in WMI rats. A Representative tracking from each group in the MWM test on day 6 (small circles, location of the platform; blue and red points, start and end locations of the rats, respectively). B Average latency to find a hidden platform during the first 5 days of training in the directional navigation experiment for each group. C Number of platform crossings in the spatial exploration experiment on day 6 when the platform was removed. D The time spent in the target quadrant on day 6 of the MWM. E Forelimb asymmetry score in cylinder test of each group. F Mean time to remove the patch in the adhesive removal test of each group. n = 8 for each group. Data are presented as the mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. Ctrl group; #P < 0.05, ##P < 0.01, ####P < 0.0001 vs. vehicle group; &P < 0.05 vs. ZJU-37 group; â–³P < 0.05 vs.hOPCs group

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