Skip to main content
Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Melatonin contributes to the hypertrophic differentiation of mesenchymal stem cell-derived chondrocytes via activation of the Wnt/β-catenin signaling pathway

Fig. 3

Melatonin decreases collagen-II expression and induces collagen-X expression during hypertrophy. a Immunohistochemical staining of Col-II in aggregates after hypertrophy differentiation for 3 weeks. Scale bar = 200 μm. b Gray value of Col-II staining in induced cartilage tissues. c Gray value for Col-II staining in a single chondrocyte. d Immunohistochemical staining of Col-X in aggregates after hypertrophy differentiation for 3 weeks. Scale bar = 200 μm. e Gray value of Col-X staining in induced cartilage tissues. f Gray value for Col-X staining in a single chondrocyte. *P < 0.05, **P < 0.01

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512