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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Melatonin contributes to the hypertrophic differentiation of mesenchymal stem cell-derived chondrocytes via activation of the Wnt/β-catenin signaling pathway

Fig. 6

Melatonin promotes the nuclear translocation of β-catenin in the C3H10T1/2 cell line. a Immunofluorescence staining of β-catenin in C3H10T1/2 cells treated with or without 100 nM melatonin, the Wnt/β-catenin signaling pathway inhibitor XAV-939 or the agonist CHIR-90021. Scale bar = 100 μm. b, d Expression of β-catenin in nuclear and cytoplasmic components of cells treated as indicated. c, e Quantitative analyses of β-catenin expression levels in nuclear and cytoplasmic components from the cells from b and d. *P < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512