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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Antifibrotic effect of lung-resident progenitor cells with high aldehyde dehydrogenase activity

Fig. 6

Detection of transferred donor CD45/ALDHbr cells in the recipient lung. A Representative images of flow cytometry of lung CD45 cells in donor mCherry-expressing mice. B Flow cytometry of lung CD45 cells in recipient BLM-treated C57BL/6 mice transferred with PBS alone, donor mCherry+/CD45/ALDHdim cells, and donor mCherry+/CD45/ALDHbr cells. Recipient lungs were harvested on the day following the cell transfer (day 3, 3 days after BLM-treatment). C Flow cytometry of lung CD45/ALDHbr cells in recipient BLM-treated C57BL/6 mice transferred with PBS alone, donor mCherry+/CD45/ALDHdim cells, and donor mCherry+/CD45/ALDHbr cells. Recipient lungs were harvested the next day and 5 days after cell transfer (days 3 and 7). D Histological analysis of mCherry immunostaining in lungs obtained from mCherry-expressing mice (positive control) and wild-type C57BL/6 mice (negative control). E Representative images of mCherry immunostaining in lungs obtained from recipient BLM-treated wild-type C57BL/6 mice transferred with mCherry+/CD45/ALDHbr cells

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