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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Intratracheal transplantation of trophoblast stem cells attenuates acute lung injury in mice

Fig. 1

Administration of TSCs during ALI attenuates infiltration of inflammatory cells. Male C57BL/6 mice received PBS (sham) or BLM (ALI) intratracheally. At day 3 after exposure, sham mice were administrated intratracheally with PBS (sham + PBS), and ALI mice with PBS (ALI + PBS), FBs (ALI + FB) or TSCs (ALI + TSC). Lung tissue and BALFs were collected at day 7. ad Representative images of H&E staining of the lungs in each group. eh Representative images of immunostaining for CD45 (brown) in each group, and the lung sections were counterstained with methyl green (blue). Scale bars represent 50 µm. i Quantitation of CD45 immunostaining. jl Quantification of total cell number (j, n = 5 ~ 6 for each group), macrophages (k, n = 3 ~ 6 for each group) and neutrophils (l, n = 3 ~ 6 for each group) in BALF, with the data presented as mean ± SEM. One-way analysis of variance was performed for il. *P < 0.05 versus sham group, &P < 0.05 versus ALI + PBS group, $P < 0.05 versus ALI + FB group, #P = 0.05 versus sham group

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