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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Feline adipose-derived mesenchymal stem cells induce effector phenotype and enhance cytolytic function of CD8+ T cells

Fig. 5

Feline ASCs upregulate the expression of Granzyme B, IL-2 and KLRG-1. A upregulation of granzyme B at 24 h from PBMCs in co-culture with ASCs in comparison with activated PBMCs alone (n = 6, p-value = 0.03) B upregulation of granzyme B, IL-2 and KLRG-1 at 96 h from bead-enriched CD8+ T cells in co-culture with ASCs (n = 6, p-value = 0.002, 0.03 and 0.002 respectively). IL-2 interleukin 2, KLRG-1 killer cell lectin-like subfamily G1

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