Fig. 7

Matrigel plug assay showed proangiogenic properties of PBS, ADSC and P-ADSC in vivo. A Matrigel plugs derived from different groups. Matrigel mixed with PBS, ADSC and P-ADSC was subcutaneously injected into the abdomen of mouse. The plugs were harvested at 14 days after implantation. B, C CD31 and α-SMA immunostaining of Matrigel plug sections and positive staining showed in brown. P-ADSC group showed more blood vessels formation than PBS and ADSC groups; α-SMA, alpha-smooth muscle actin. D Statistical analysis of vessels number in Matrigel plugs. *p < 0.05, **p < 0.01 versus saline, #p < 0.05, ##p < 0.01 versus ADSC. P-ADSC PEV treated ADSCs