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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: The effect of genetically modified platelet-derived growth factor-BB over-expressing mesenchymal stromal cells during core decompression for steroid-associated osteonecrosis of the femoral head in rabbits

Fig. 8

Assessment of angiogenesis. Immunohistochemistry was performed to stain for CD31+ microvessels within the femoral head. a Representative images of each treatment group are shown. b Within the subchondral bone, the bone surrounding the bone tunnel area, and within the bone tunnel area, the PGK-PDGF-BB-MSC group demonstrated a significantly greater number of CD31+ microvessels than the other treatment groups (P < 0.01 for all). Scale bar: 100 µm. CD31, cluster of differentiation 31; CD core decompression, HG hydrogel, MSC mesenchymal stromal cell, PGK-PDGF-BB-MSC genetically modified phosphoglycerate kinase promoter platelet-derived growth factor-BB over-expressing MSC. **P < 0.01, ***P < 0.001, ****P < 0.0001

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Stem Cell Research & Therapy

ISSN: 1757-6512