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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Human bone marrow-derived mesenchymal stromal cells cultured in serum-free media demonstrate enhanced antifibrotic abilities via prolonged survival and robust regulatory T cell induction in murine bleomycin-induced pulmonary fibrosis

Fig. 6

Tregs depletion abolished the antifibrotic effect of SF-MSCs during BLM-induced pulmonary fibrosis. A Experimental scheme of Treg depletion using the PC61 Ab in vivo. iv, intravenous injection. ip, intraperitoneal injection. B The percentage of blood or lung Tregs at 14 days after BLM OA in mice treated with or without PC61 Ab and SF-MSCs (n = 5 per group). C The hydroxyproline content in each group (n = 5–11 per group). Data are presented as means ± SD. *P < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512