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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Knockdown of SERPINB2 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells via activation of the Wnt/β-catenin signalling pathway

Fig. 2

Exogenous recombinant SerpinB2 inhibited mineralization and ALP activity. a, b Recombinant SerpinB2 inhibited hBMSC mineralization. hBMSCs were incubated with different concentrations of Serpinb2 during osteogenesis for 15 days. Calcium deposits level were colored by Alizarin Red S staining. SerpinB2 inhibited mineralization significantly compared with the control group. Scale bars, 50 um. c, d Recombinant SerpinB2 inhibited the ALP activity of hBMSCs. hBMSCs were incubated with different concentrations of SerpinB2 during osteogenesis for 6 days. ALP activity was detected by ALP staining. SerpinB2 inhibited the ALP activity significantly compared with the control group. Scale bars, 50 um

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Stem Cell Research & Therapy

ISSN: 1757-6512