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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Knockdown of SERPINB2 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells via activation of the Wnt/β-catenin signalling pathway

Fig. 6

SERPINB2 knockdown in the fracture sites promoted the expression of RUNX2 and SP7. a, b Immunofluorescence analysis for bone healing. Immunofluorescence assay to asses expression of osteo-specific proteins in the fracture sites at day 14. SERPINB2 konckdown (SI) group showed increased expression of RUNX2 and SP7 compared to those in the controlled groups. Scale bars, 500 um. Data are expressed as mean ± SD. Assays were performed in triplicate. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001 compared with the control group

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Stem Cell Research & Therapy

ISSN: 1757-6512