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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Transplantation of mesenchymal stem cells ameliorates systemic lupus erythematosus and upregulates B10 cells through TGF-β1

Fig. 2

Flow cytometric analysis of B10, Th1, Th2, Th17 and Treg cells in the spleens of MRL/lpr mice after MSCs transplantation. a, c, e, g, i Representative FACS images of CD19+IL-10+ (B10 cells), CD4+IFN-γ+ (Th1 cells), CD4+IL4+ (Th2 cells), CD4+IL17+ (Th17 cells) and CD4+Foxp3+ (Treg cells). For B10 cells detection, B cells were isolated from the spleen of mice and were stimulated for 48 h with sCD40 Ligand and CpG. b, d, f, h, j Percentages of B10, Th1, Th2, Th17 and Treg cells in the spleens of MRL/lpr mice with or without MSCs transplantation. Data are mean ± SD. PBS (n = 7), MSCs (n = 7). *p < 0.05. PBS, phosphate buffered saline; MSCs, umbilical cord mesenchymal stem cells

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