Evaluation of the effect of donor weight on adipose stromal/stem cell characteristics by using weight-discordant monozygotic twin pairs

Table 1 Clinical characteristics of the MZ twins

Variable	Weight-discordant pairs (ΔBMI > 3 kg/m²)
	Leaner cotwin			Heavier cotwin			p Value
	Median	Min	Max	Median	Min	Max	p Value
BMI	23.3	21.5	39.9	26.8	25.8	44.2	0.043
Cholesterol (mmol/l)	3.9	3.0	4.7	5.0	3.0	6.9	0.276
Triglycerides (mmol/l)	0.6	0.5	0.8	1.4	0.5	2.7	0.225
HDL (mmol/l)	1.7	1.3	2.1	1.3	0.5	2.2	0.138
LDL (mmol/l)	2.0	1.6	3.0	3.4	1.6	4.5	0.080
hs-CRP (mg/l)	0.4	0.2	3.9	0.8	0.2	7.0	0.225
HOMA-IR	0.8	0.3	1.0	1.8	0.6	2.7	0.138
Plasma leptin (ng/ml)	10.0	0.7	77.6	22.1	5.2	55.7	0.500
Plasma adiponectin (ng/ml)	5050	3700	7710	4030	1310	4930	0.043

Wilcoxon’s signed-rank test was used to compare the values of the leaner vs heavier cotwin. A p value less than 0.05 was considered significant (shown in bold). HDL = high-density lipoprotein, LDL = low-density lipoprotein, hs-CRP = high-sensitivity C reactive protein, HOMA-IR = insulin resistance index

ISSN: 1757-6512