Fig. 1

The dynamic of histopathological changes and liver regeneration in a single infection mouse model with S. japonicum. A Representative images of HE staining at different infection time points. Arrows indicate the necrosis. B The statistical analysis of percent of granulomas area. n = 7 in uninfected group, n = 5 in each infected group. C Representative images of Masson staining. D The statistical analysis of percents of fibrosis area. n = 7 in uninfected group, n = 5 in each infected group. E Representative images of TUNEL staining. n = 3 mice/group. F Representative images of CD45 staining. n = 3 mice/group. G Representative images of F4/80 staining. n = 3 mice/group. H The expression level of albumin in serum. n = 7 in uninfected group, n = 5 mice in each infected group. Images were captured by an inverted microscope (Olympus, BX63, Tokyo, Japan). *P < 0.05, **P < 0.01, ***P < 0.001