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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Exosomes secreted by FNDC5-BMMSCs protect myocardial infarction by anti-inflammation and macrophage polarization via NF-κB signaling pathway and Nrf2/HO-1 axis

Fig. 5

FNDC5-MSCs‐Exo reduced the inflammation by suppressing the NF‐κB signaling pathway. a Representative Western blot analysis of p-IκBα and IκBα in RAW264.7 cells under different conditions. Representative semi-quantification analysis of p-IκBα (b) and IκBα (c). d Cytoplasmic and nuclear proteins were collected and extracted to measure IκBα and NF‐κB p65. GAPDH (e, f) and Histone3 (g) were used as normalized cytoplasmic and nuclear protein. Data are expressed as the means ± SEM; n = 5; *P < 0.05.

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