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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Regulation of the integrin αVβ3- actin filaments axis in early osteogenesis of human fibroblasts under cyclic tensile stress

Fig. 3

Actin filaments regulated early stage of osteogenic differentiation induced by CTS via integrin αVβ3 activation in fibroblasts. a Protein expression of β-actin under CTS for 4 d and 7 d. b mRNA expression of β-actin under CTS for 4 d and 7 d. c Protein expression of β-actin under CTS in the GM and RGDyk groups. d mRNA expression of β-actin under CTS in the GM and RGDyk groups. e Protein expression of β-actin under CTS in the GM, NC, shRNA-integrin αV and shRNA-integrin β3 groups. f mRNA expression of β-actin under CTS in the GM, NC, shRNA-integrin αV and shRNA-integrin β3 groups. g Protein expression of β-actin under CTS in the CTS and Cyto D groups. h Immunofluorescence of F-actin under CTS in the GM, CTS, NC, shRNA-integrin αV and shRNA-integrin β3 groups for 7 d. Scale bar, 50 μm

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