Skip to main content
Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis

Fig. 5

Transplantation of sTNFRII-MSC regulates the cytokine and autoantibody production in CIA mice. ae Cytokine levels in serum of CIA mice transplanted with sTNFRII-MSC. TNF-α (a), IFN-γ (b), IL-4 (c), IL-10 (d), and IL-17 (e) levels in the serum of CIA mice were determined by ELISA (n = 5). fh Autoantibody levels in serum of CIA mice transplanted with sTNFRII-MSC. Levels of IgG1 (f), IgG2a (g) and anti-CII autoantibody (h) in the serum of CIA mice were determined by ELISA (n = 5). Data are presented as the mean ± SD values. *p < 0.05, **p < 0.01

Back to article page