Fig. 5From: sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritisTransplantation of sTNFRII-MSC regulates the cytokine and autoantibody production in CIA mice. a–e Cytokine levels in serum of CIA mice transplanted with sTNFRII-MSC. TNF-α (a), IFN-γ (b), IL-4 (c), IL-10 (d), and IL-17 (e) levels in the serum of CIA mice were determined by ELISA (n = 5). f–h Autoantibody levels in serum of CIA mice transplanted with sTNFRII-MSC. Levels of IgG1 (f), IgG2a (g) and anti-CII autoantibody (h) in the serum of CIA mice were determined by ELISA (n = 5). Data are presented as the mean ± SD values. *p < 0.05, **p < 0.01Back to article page