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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Activation of the EGFR-PI3K-CaM pathway by PRL-1-overexpressing placenta-derived mesenchymal stem cells ameliorates liver cirrhosis via ER stress-dependent calcium

Fig. 6

Graphical abstract describing improved hepatic functions and decreased ER stress and calcium influx by PD-MSCPRL−1 transplantation in hepatocytes from a rat BDL model via the EGFR-PI3K-CaM signaling pathway. BDL, bile duct ligation; CaM, calmodulin; EGFR, epidermal growth factor receptor; PRL-1, phosphatase of regenerating liver-1; PI3K, phosphatidylinositol-3-kinase

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Stem Cell Research & Therapy

ISSN: 1757-6512