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Table 2 Some resources and features of stem cells which contribute in endometrium regeneration

From: Stem cell-based therapy for ameliorating intrauterine adhesion and endometrium injury

Stem cell Major source Properties References
BMSCs Bone marrow Multi-potent, highly proliferative, good migration ability, self-renewing, immunomodulatory properties [46, 47]
Autologous adult stem cells Bone marrow Donor-derived bone marrow cells have been identified in human uterine endometrium (both stromal and epithelial cells were derived from bone marrow origin). It is unknown whether these cells originate from bone marrow mesenchymal stem cells or circulating endometrial cells originally derived from the endometrium and harbored in bone marrow [48]
eMSCs Endometrium Multi-potent, highly proliferative, self-renewing; coexpression of CD140b (PDGFR-β) and CD146, or expression perivascular markers SUSD2 (W5C5 antibody) SUSD2 [49,50,51]
ESP Endometrium Heterogeneous, presumably containing stem/progenitor cells of each endometrial cell lineage; produce endometrial endothelial, epithelial, and stromal cells in vitro and in vivo [49, 52, 53]
UC-MSCs Umbilical cord Derived from the mesoderm in early development; low immunogenicity; multi-potent cells; high self-renewal ability; multi-differentiation; high proliferative potential [54,55,56]
ADSCs Adipose tissue Abundant sources; easy sampling; self-renewal; multi-potential differentiation; strong proliferation ability [57,58,59,60,61]
ESCs Embryo Pluripotent stem cells derived from the inner cell mass of a blastocyst; high telomerase activity; significant long-term proliferation potential [62, 63]
ASCs Amniotic membrane Inflammatory suppression, angiogenesis promotion, anti-oxidative stress [64, 69]