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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Wharton’s jelly mesenchymal stem cells embedded in PF-127 hydrogel plus sodium ascorbyl phosphate combination promote diabetic wound healing in type 2 diabetic rat

Fig. 2

Histology analysis of the dermis regeneration and collagen deposition. a Hematoxylin and eosin staining in diabetic wound bed and surrounding normal tissues were analyzed at day 14 after transplantation. Scar bar: 500 μm. b The quantitative data of the dermis thickness in each group were showed at day 14 after transplantation. Error bars represent mean ± SEM; n = 8 independent experiments. Significance was determined using one-way ANOVA. ***p < 0.001. c The quantitative data of the number of newborn hair follicles in each group at day 14 post-transplantation per field. Error bars represent mean ± SEM; n = 8 independent experiments. Significance was determined using one-way ANOVA. ***p < 0.001. d The quantitative data of the scar width in each group were showed at day 14 post-transplantation. Error bars represent mean ± SEM; n = 8 independent experiments. Significance was determined using one-way ANOVA. ***p < 0.001. e Masson’s trichrome staining of diabetic wound bed and surrounding normal tissues was showed at day 14 after transplantation. Scar bar: 500 μm. N, normal skin tissue, shown on both sides of the black imaginary line; H, healed skin tissue, shown between black and red imaginary lines; W, wound bed, unhealed skin tissue, shown between the red imaginary lines

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