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Table 3 Delivery of DRUG by MSC-EXOs

From: Mesenchymal stem cells-derived exosomes for drug delivery

Aim Exosomes origin Loading methods Administration route Model DRUG References
Breast cancers HucMSC Incubation Intravenous injection Mice Paclitaxel [115]
Breast cancers MSC Electroporation In vitro cell experiment   Doxorubicin [114]
Hepatocellular carcinoma BMSC Electroporation Intravenous injection Mice Norcantharidin (NCTD) [117]
Osteosarcoma BMSC Dialyze In vitro cell experiment   Doxorubicin [119]
Pancreatic cancer BMSC Electroporation Intravenous injection Mice Gemcitabine monophosphate(GEMP) [120]
Oral squamous cell carcinoma MSC Incubation Injected subcutaneously Mice Cabazitaxel (CTX) [116]
Several cancer cell lines MSC Sonication In vitro cell experiment   Honokiol [118]