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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: TM9SF4 is a novel regulator in lineage commitment of bone marrow mesenchymal stem cells to either osteoblasts or adipocytes

Fig. 3

TM9SF4 depletion delays bone loss during osteoporosis. A, B Micro-CT analysis of trabecular structure in femurs from normal adult mice and OVX mice. Ctrl, non-surgery group; OVX, ovariectomy group. BV/TV, bone volume/total volume; Tb.N, trabecular number; Tb.Sp, trabecular spacing; Tb.Th, trabecular thickness. Error bars represent mean ± SD, n = 6 in Ctrl group, n = 8 in OVX group, ***P < 0.001, ****P < 0.0001, ns = not significant. C, D H&E staining and toluidine blue staining on the top of tibias. Scale bars = 150 µm. E IHC staining of Collagen1α1. Scale bars = 150 µm

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