Fig. 1

Myeloid lineage analysis in the peripheral blood and spleen of Casepase-3 gene knockout mice. A Analysis of peripheral blood counts of red blood cells (RBC), white blood cells (WBC), and platelets (PLT) in wild-type (WT) and Caspase-3^−/− (KO) mice (n = 4). B Spleen from WT and Caspase-3 KO mice and analysis of spleen index (the ratio of spleen/body weight) in WT and Caspase-3 KO mice (n = 6). C The H&E staining of spleen sections from WT and Caspase-3 KO mice. D The immunofluorescence staining of spleen sections from WT and Caspase-3 KO mice (DAPI: blue; CD11b: red). E Flow cytometry analysis of the percentage of CD11b⁺/Gr-1⁺ myeloid cells in the spleen of WT and Caspase-3 KO mice (n = 3). F Flow cytometry analysis of the percentage of CD11b⁺/Gr-1⁺ myeloid cells in the peripheral blood of WT and Caspase-3 KO mice (WT: n = 5; KO: n = 4). All data are presented as mean ± SEM. ns: not significant, *P < 0.05