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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Molecular differences of adipose-derived mesenchymal stem cells between non-responders and responders in treatment of  transphincteric perianal fistulas

Fig. 2

Cellular characteristics of AT-MSCs from responders and non-reponders in fistula treatment. AT-MSCs were established from non-responders (n = 15) and responders (n = 12) in AT graft fistula treatment. The cells were examined in undifferentiated state in passage 1. A Short-term proliferative rate, area under the curve (AUC) and cell proliferation rate measured by MTT assay (from left to right) of AT-MSCs in non-responder and responder group (n = 12–15). *p < 0.05, non-responders versus responders. Screening of stem cell surface marker expression, such as B CD44, CD90, CD105 and C CD49a, LEPR, and SOX2 measured using flow cytometry in AT-MSCs isolated from non-responder and responder subjects (n = 12–15). Data are presented as means ± SEM; *p < 0.05, non-responders versus responders, (two-tailed unpaired Student’s t test)

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