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Table 3 EV-hydrogel delivery systems

From: Emerging concepts in the treatment of optic neuritis: mesenchymal stem cell-derived extracellular vesicles

Type of EV Hydrogel Material Application References
BMSC-EV Thiol-modified hyaluronan, heparin, gelatin, and polyethylene glycol Increased levels in white matter [179]
HMSC-EVs Photoinduced imine crosslinking hydrogel Cartilage regeneration and repair [180]
ADSC-EVs Pluronic F127, oxidative hyaluronic acid, and Poly-ε-L-lysine Chronic diabetic wound healing [181]
UMSC-EVs Silk fibroin hydrogel Aging-induced vascular dysfunction [182]
PMSC-EVs Chitosan hydrogel Hindlimb Ischemia [133]
GMSC-EVs Chitosan and silk-based hydrogel Diabetic wound healing [183]
UMSC-EVs PA-GHRPS and NapFF peptide hydrogel Myocardial infarction [182]
  1. ADSC: Adipose tissue-derived mesenchymal stem cells; GMSC: Gingival mesenchymal stem cells; PMSC: Placental mesenchymal stem cells; UMSC: Umbilical cord-derived mesenchymal stem cells