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Table 3 EV-hydrogel delivery systems

From: Emerging concepts in the treatment of optic neuritis: mesenchymal stem cell-derived extracellular vesicles

Type of EV

Hydrogel Material

Application

References

BMSC-EV

Thiol-modified hyaluronan, heparin, gelatin, and polyethylene glycol

Increased levels in white matter

[179]

HMSC-EVs

Photoinduced imine crosslinking hydrogel

Cartilage regeneration and repair

[180]

ADSC-EVs

Pluronic F127, oxidative hyaluronic acid, and Poly-ε-L-lysine

Chronic diabetic wound healing

[181]

UMSC-EVs

Silk fibroin hydrogel

Aging-induced vascular dysfunction

[182]

PMSC-EVs

Chitosan hydrogel

Hindlimb Ischemia

[133]

GMSC-EVs

Chitosan and silk-based hydrogel

Diabetic wound healing

[183]

UMSC-EVs

PA-GHRPS and NapFF peptide hydrogel

Myocardial infarction

[182]

  1. ADSC: Adipose tissue-derived mesenchymal stem cells; GMSC: Gingival mesenchymal stem cells; PMSC: Placental mesenchymal stem cells; UMSC: Umbilical cord-derived mesenchymal stem cells