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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: HO-1/BMMSC perfusion using a normothermic machine perfusion system reduces the acute rejection of DCD liver transplantation by regulating NKT cell co-inhibitory receptors in rats

Fig. 1

The DCD LT model and BMMSC colonization in the liver. A The general appearance of a normal liver. B At 30 min after DCD, hepatic congestion was severe, exhibiting purple-red appearance, rounded edges, and slight edema. C The appearance of the liver preserved by the SCS method was characterized by flaky congestion and edema. D The liver preserved by the NMP method has a uniform color without edema and congestion. E and F The “two-cuff method” successfully completed rat LT. The in vivo imaging system detects the fluorescence intensity of GFP/BMMSCs (G) and HO-1/BMMSCs (H) (indicated by the white dotted line). A fluorescence microscope was used to observe the control group (I) and the number of colonizing GFP/BMMSCs (J) and HO-1/BMMSCs (K) in the liver (indicated by the white arrow) on the frozen sections of the liver and the statistical results (L). *P < 0.05

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