Fig. 6

Transplanted sevoflurane preconditioned MSCs reduced myocardial infarct areas and induced anti-inflammatory response. Representative images and quantification of AAR and infarct size were at 3 d after I/R were measured by Evans blue and TTC (a). AAR was shown as percentage of the respective total heart areas and infarct size was expressed as percentage of AAR. Blue was unaffected heart muscle; red plus white was risk zone; white was infarcted tissue. LDH, cTnI, IL-10, IL-1β and TNF-α levels of mice blood serum after I/R were detected by a commercial kit at 3 d after I/R (b). Data are shown as Mean ± SEM, n = 5 per group. ^***P < 0.001 vs Sham; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 versus I/R; ⁺P < 0.05, ⁺⁺P < 0.01 versus MSC