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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Genome-wide differential expression profiling of lncRNAs and mRNAs in human induced pluripotent stem cell-derived endothelial cells exposed to e-cigarette extract

Fig. 5

Correlation between top 5 significantly upregulated and downregulated lncRNAs and mRNA transcripts. LncRNA-mRNA co-expression network was constructed with top 5 up- and downregulated lncRNAs and 353 associated mRNAs. Red nodes, blue nodes, and yellow nodes correspond to upregulated lncRNAs, downregulated lncRNAs, and coding genes/mRNAs. Solid lines signify a positive Pearson’s correlation coefficient (PCC), and dotted lines signify negative PCC. Coding–noncoding pairs are defined as co-expressing pairs if ∣PCC∣  ≥ 0.9 and p ≤ 0.05

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