Fig. 1
From: Induction of meiosis by embryonic gonadal somatic cells differentiated from pluripotent stem cells
Transcriptome of fetal and adult gonadal somatic cells. A Time-course line chart showing changes in gene expression during embryonic development. Cluster 1, 2, 3, and 4 represent E12.5, E13.5, E16.5, and P6w, respectively. B Enriched terms in each stage. Genes upregulated in E12.5_GSCs were clustered in mesonephric development, response to retinoic acid, Wnt signaling pathway, and Hippo signaling pathways. C KEGG analysis of enriched genes in E12.5_GSCs. Wnt, Hippo, cAMP signaling pathway were clustered in E12.5 stage. D Pheatmap showing genes enriched in Wnt signaling pathway. E GO analysis of enriched genes in E12.5_GSCs, response to retinoic acid, mesonephric development, Wnt-related signaling pathway were clustered in E12.5_GSCs. F Pheatmap showing genes enriched in response to retinoic acid