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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Human MuStem cells repress T-cell proliferation and cytotoxicity through both paracrine and contact-dependent pathways

Fig. 1

Phenotypic profile of human MuStem cells focused on immune-cell-related markers. Cell events were first selected upon their size and granularity (forward scatter vs. side scatter density plot), while the FSC-A/FSC-H plot on gated events allowed identification of single cells. Flow cytometry comparison of: a HLA class I (HLA-ABC, HLA-G1 and HLA-E) and class II (HLA-DQ, -DR and -DP) molecules; b co-stimulatory molecules CD80, CD86 and CD40; c programmed death ligand (PDL)-1 and -2; d TIGIT receptor CD112 and CD155; and e intracellular cell adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule (VCAM-1) in hMuStem cells cultured in basal condition (unstimulated) or after stimulation with TNF-α/IFN-γ (pro-inflammatory condition). When an expression is detected, mean ± SEM of positive cells and rMFI are reported on the top right corner. Results of one representative cell batch out of five independent batches are presented

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