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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: UM171A-induced ROS promote antigen cross-presentation of immunogenic peptides by bone marrow-derived mesenchymal stromal cells

Fig. 6

Anti-tumoral response induced by therapeutic vaccination using UM171a-treated MSCs. A Schematic diagram showing the experimental design used for therapeutic vaccination. B Assessment of tumor growth overtime following administration of DMSO-treated MSCs (green) or UM171a-treated MSCs (red) pulsed with OVA. Mice with injected EG.7 tumors are depicted in black. C Kaplan–Meier survival curve of the experiment shown in panel B. D Secretome profiling conducted on DMSO- (black) versus UM171a-treated MSCs (blue) cultured for 72 h. For this panel, n = 6/group with ***P < 0.001

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Stem Cell Research & Therapy

ISSN: 1757-6512