SCT mean (SD) [% > DR] | DEX mean (SD) [% > DR] | SCT T2 versus T1 difference | DEX versus SCT for T2 and T1 difference | |||||
---|---|---|---|---|---|---|---|---|
T1 | T2 | T1 | T2 | Effecta [95% CI] | P value (adjusted) | Effectb [95% CI] | P value (adjusted) | |
IL-1β* | 22.510 (17.260) | 24.078 (34.070) | 27.651 (30.293) | 11.089 (16.941) | 0.608 [0.281; 1.315] | 0.19 (0.4) | 0.472 [0.171; 1.307] | 0.14 (0.3) |
IL-4* | 0.140 (0.106) | 0.190 (0.385) | 0.116 (0.122) | 0.182 (0.359) | 0.812 [0.329; 2.003] | 0.6 (0.7) | 0.796 [0.252; 2.510] | 0.7 (0.8) |
IL-8* | 7470.490 (5017.252) | 8013.460 (11,453.562) | 10,222.300 (13,818.670) | 5742.500 (4475.492) | 0.607 [0.296; 1.245] | 0.2 (0.4) | 1.137 [0.445; 2.905] | 0.8 (0.8) |
IL-17* | 0.019 (0.014) | 0.009 (0.010) | 0.020 (0.021) | 0.005 (0.008) | 0.409 [0.201; 0.831] | 0.02 (0.05) | 0.432 [0.167; 1.120] | 0.08 (0.2) |
TNFα* | 146.908 (140.452) | 112.709 (119.865) | 113.907 (67.441) | 78.013 (48.822) | 0.780 [0.487; 1.250] | 0.3 (0.4) | 0.803 [0.442; 1.458] | 0.4 (0.7) |
INFy* | 2.831 (3.534) | 1.610 (1.330) | 2.113 (2.654) | 1.551 (1.587) | 0.665 [0.342; 1.290] | 0.2 (0.4) | 0.782 [0.330; 1.850] | 0.5 (0.7) |
eIL-1β* | 370.062 (293.004) [90] | 279.188 (156.496) [90] | 217.321 (84.624) [80] | 203.012 (84.247) [60] | 0.699 [0.586; 0.833] | < 0.001 (< 0.001) | 0.828 [0.678; 1.011] | 0.06 (0.2) |
eIL-4* | 340.817 (291.316) [100] | 257.304 (165.533) [100] | 198.584 (97.086) [90] | 203.012 (84.247) [60] | 0.555 [0.422; 0.731] | < 0.001 (< 0.001) | 0.676 [0.482; 0.949] | 0.02 (0.1) |
eTNFα* | 1102.100 (878.340) [100] | 740.418 (759.764) [100] | 609.070 (606.676) [100] | 473.075 (378.766) [100] | 0.553 [0.376; 0.812] | 0.005 (0.02) | 1.765 [1.033; 3.014] | 0.04 (0.1) |