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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: First-in-human autologous oral mucosal epithelial sheet transplantation to prevent anastomotic re-stenosis in congenital esophageal atresia

Fig. 4

Transplantation of epithelial cell sheets onto anastomotic stenosis using a dedicated device. A Contrast study findings of the patient's esophagus before EBD. The area indicated by the arrows is anastomotic stenosis. B Endoscopic image of the anastomotic stenosis before EBD. C Contrast study findings of the esophagus during EBD. The area indicated by the arrows was thought to be anastomotic stenosis, which could not be fully expanded due to scar contracture. D Endoscopic image of the esophagus dilated by balloon and lacerations therein. E–G Transplantation of cell sheets onto laceration areas caused by EBD using a dedicated device. A cell sheet was set on the surface of the balloon (arrowhead) at the tip of the device (F), and by expanding this balloon, the cell sheet was attached to the lacerated area on the esophageal mucosa. The area surrounded by the white dashed line shows the transplanted cell sheet (G)

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Stem Cell Research & Therapy

ISSN: 1757-6512