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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Prednisolone and mesenchymal stem cell preloading protect liver cell migration and mitigate extracellular matrix modification in transplanted decellularized rat liver

Fig. 5

The PAS staining of the representative sample of the BM-MSC-loaded transplant showed reorganization of the hepatocyte-like cells in the form of hepatic cords (A). * indicates the intact part of the liver. The square in Fig A was examined with higher magnification and showed the reorganized hepatic cords (B). The higher magnification of this part (C) revealed the cells with hepatocyte phenotype (arrow) were arranged in the form of hepatic cords and the sinosuides could be observed between them. Arrowhead shows the nuclei of the endothelial cells. Comparing the PAS reaction of the hepatocytes in the intact part of the liver (D) and migrating hepatocyte-like cells in the scaffold (C) revealed that they had not stored glycogen yet; therefore, they were not functional. The distribution of the bile duct by tessellation method (E)

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Stem Cell Research & Therapy

ISSN: 1757-6512