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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Synergistic regenerative therapy of thin endometrium by human placenta-derived mesenchymal stem cells encapsulated within hyaluronic acid hydrogels

Fig. 2

The retention time and distribution of HP-MSCs in the endometrium. A Schematic presentation of intrauterine instillation and its corresponding detection methods. Equal cell quantities of HP-MSCs and HP-MSCs-HA labelled by CM-DiD or CM-DiR were implanted to the certain uterus (2 × 105 per/uterus). B The mouse on the left was the untreated control group to eliminate the interference of autofluorescence, while the mouse on the right was the treatment group. The retention time of HP-MSCs was observed by an IVIS Spectrum Imaging System at the different time points (1, 3, 7, 14, 28, and 35 days) after transplantation. C The total radiant efficiency of the treated uterus was measured and calculated. Data were presented as mean ± SEM (n = 3). ** indicates P < 0.01. D Ex vivo frozen section of the uterus showed the retention of HP-MSCs, which were labelled with CM-DiD (red). The nuclei of cells were labelled with DAPI (blue)

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