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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Synergistic regenerative therapy of thin endometrium by human placenta-derived mesenchymal stem cells encapsulated within hyaluronic acid hydrogels

Fig. 4

The histological analysis of endometrium for the five mouse groups after different treatments. A H&E staining results of the five groups for evaluating the endometrial thickness and number of glands. B Masson staining results of the five groups for evaluating the fibrosis status of the endometrium. C Immunohistochemical Ki67 expression of the five groups for evaluating the proliferation of endometrial cells. D Immunohistochemical VEGF expression of the five groups for evaluating the angiogenesis of endometrium. E Average endometrial thickness and statistical analysis (± SEM) of the five groups. * indicates P < 0.05, ** indicates P < 0.01, *** indicates P < 0.001, n = 6. F Average gland number and statistical analysis (± SEM) of the five groups. * indicates P < 0.05, n = 6. G Average fibrosis area and statistical analysis (± SEM) of the five groups. The ratio of the fibrotic area = endometrial fibrotic area/endometrial area. * indicates P < 0.05, ** indicates P < 0.01, *** indicates P < 0.001, **** indicates P < 0.0001, n = 6. H Statistic analysis of IRS of Ki67 in the endometrium of the five groups. * indicates P < 0.05, ** indicates P < 0.01, n = 6. I Statistic analysis of IRS of VEGF in the endometrium of the five groups. * indicates P < 0.05, ** indicates P < 0.01, n = 6

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