Fig. 2

Clinical trials based on targeting EGFR family members, especially HER2, using human CAR T cells registered in ClinicalTrials.gov (September 2021). The schematic presents clinical trials respecting the treatment of EGFR-positive tumors using CAR T cells depending on the study phase (A), target antigen (B), study status (C), tumors (D), participant number (E), and study location (F). Human epidermal growth factor receptor 2 (HER2), Epidermal growth factor receptor (EGFR)