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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Matrix vesicles from dental follicle cells improve alveolar bone regeneration via activation of the PLC/PKC/MAPK pathway

Fig. 3

DFCs-derived MMVs and CRMVs enhance osteogenic differentiation of DFCs. A Representative images of alizarin red s staining of the gross view and microscopy observation after culturing for 14 days. Scale bar: 500 μm. B The optical density value of the dissolved mineral nodules measured by a spectrophotometer at 562 nm. Quantitative comparisons were made between each experimental group and the control. C Western blot analysis of osteogenic proteins (ALP, OCN, OPN, and MMP-2) in DFC lysed after the induction of different groups for 4 days, and GAPDH was set as the internal control. D Quantitative statistics of the related proteins. *p < 0.05, **p < 0.01, ***p < 0.001

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