Fig. 7

miR-144-3p promoted tendon repair via targeting ARID1A in tenocytes. A ARID1A was predicted as a potential target of miR-144-3p by all three bioinformatic programs (TargetScan, miRDB and DIANA TOOLS). B Plasmid vectors of ARID1A 3′UTR and its mutation. C Dual-luciferase reporter assay showed that miR-144-3p targeted ARID1A 3′UTR but not its mutation (Bars: mean ± SE; n = 3; unpaired Student’s t test: miR-NC vs. miR-144-3p in wild type groups; miR-NC vs. miR-144-3p in mutant groups, *p < 0.05). D, E miR-144-3p mimic suppressed ARID1A mRNA and protein expression in tenocytes, while miR-144-3p inhibitor removed the suppression effects (Bars: mean ± SE; n = 3; unpaired Student’s t test: mimic-NC vs. miR-144-3p mimic; inhibitor-NC vs. miR-144-3p inhibitor, *p < 0.05 and **p < 0.01)