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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Osteogenic differentiation of mesenchymal stem cells promotes c-Jun-dependent secretion of interleukin 8 and mediates the migration and differentiation of CD4+ T cells

Fig. 2

Osteogenic differentiation of MSCs impacts MSC-mediated CD4+ T cell recruitment. a CD4+ T cells were isolated from PBMCs, and the purity was assessed by flow cytometry. b After a 4-h coculture with MSCs, the number of migrated CD4+ T cells was assessed by flow cytometry. MSC osteogenic differentiation enhanced the MSC-mediated migration of CD4+ T cells, and culture supernatants showed similar results. Statistical significance among groups was determined by using SPSS. Values are presented as the mean ± SD of 12 samples per group. ns indicated P > 0.05, and * indicates P < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512