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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Abnormal respiratory progenitors in fibrotic lung injury

Fig. 1

Airway progenitors migrated from the proximal airway to the distal airway. In the healthy airway, basal cells differentiate into ciliated, goblet, tuft, and club cells. In pathogenic states, basal-like and basaloid cells populate the airway. BASCs differentiate into club and ATII cells in the middle airway. ATII cells differentiate into AEP, ATII proliferating, ATII primed, cell cycle arrest, and ATI cells. In pathological alveolar states, ATIIs differentiate into PEPs (DATPs, PATs, Krt8 + , and ADI). This figure is created with BioRender.com

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