Fig. 8
From: A dual role of HIF1α in regulating osteogenesis–angiogenesis coupling
ROS regulated the HIF1α-p53 axis. A, B 8-oHdG staining of femurs and tibias. Black bar = 100 μM; red bar = 25 μM. C Quantitative analysis of relative ROS level in YBMSCs and ABMSCs. D, E Relative SOD2 expression of H2O2-treated YBMSCs and NAC-treated ABMSCs. F Western blot analysis for HIF1α-siRNA-transfected H2O2-treated YBMSCs and NAC-treated ABMSCs. G Quantitative analysis of HIF1α. H, I Quantitative analysis of p53, VEGF, RUNX2, ALP and OSX. *p < 0.05 versus YBMSC; #p < 0.05 versus ABMSC; γp < 0.05 versus YBMSC-HIF1α-siRNA; δp < 0.05 versus ABMSC-HIF1α-siRNA